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Lareau SC, Yawn BP: Improving adherence with inhaler therapy in COPD.

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Discard after 6 weeks (50 mcg diskus) or after 2 months (100 mcg and 250 mcg diskus) from removal from protective foil pouch or when the dose counter reads “0” (whichever comes first); device is not reusable.

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Serum cortisol concentrations following 250- and 500-mcg twice-daily dosing were 10% and 21% lower than placebo, respectively, indicating a dose-dependent increase in systemic exposure to fluticasone propionate.

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Excluded were children with first wheezing episodes who had not previously received bronchodilator therapy, children who required immediate therapy with intravenous corticosteroids or intubation, children who had taken oral prednisone within seven days of the visit, children taking 1000 μg or more of inhaled beclomethasone dipropionate or budesonide per day or 500 μg or more of inhaled fluticasone per day, and children with concurrent cardiopulmonary disease, immunodeficiency, diabetes mellitus, allergy to corticosteroids, or exposure to varicella within the previous 21 days.

Review of Guidelines and the Literature in the Treatment of Acute Bronchospasm in Asthma.

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After clinic visits at 0, 4, and 8 weeks (visits 0, 1, and 2, respectively) patients were randomised to receive either fluticasone propionate 500 μg or an identical placebo twice daily administered from a metered dose inhaler and with a spacer device by using 10 tidal breaths after each of two actuations.

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Anderson P: Use of Respimat Soft Mist Inhaler in COPD patients.

Common side effects of fluticasone propionate nasal spray are headache, sore throat and nose bleed.

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice.

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COPD therapy, use of medication to treat or prevent osteoporosis should be strongly considered.

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The inhaler has a window that shows the number of doses remaining.

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Numbers at each assessment indicate number of patients for whom measurements of health status were available at that visit.

Administer fluticasone alone or in fixed combination with salmeterol (Advair HFA) as a microcrystalline suspension by oral inhalation using an oral aerosol inhaler with hydrofluoroalkane (HFA; non-chlorofluorocarbon) propellant.

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They, however, reported a trend of improvement in lung function only with medium or high doses systemic corticosteroids.

Comparison of short courses of oral prednisolone and fluticasone propionate in the treatment of adults with acute exacerbations of asthma in primary care.

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Use only a fast acting inhalation medicine for an asthma attack.

Atopic Dermatitis: Apply a thin film of Fluticasone propionate cream to the affected skin areas once or twice daily.

As a topical corticosteroid, fluticasone has potent anti-inflammatory effects in the airways through decreasing the production of any inflammatory molecules that may be present.

Long-term use of steroids may lead to osteoporosis, especially if you smoke, do not exercise, do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.

The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient.

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No increase in frequency of cardiovascular adverse reactions was observed among subjects who averaged 6 or more inhalations per day.

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Six hundred fifty (650) patients aged 4 to 11 years and 440 patients aged 12 to 17 years were studied in US clinical trials with Fluticasone Propionate Nasal Spray, USP.

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Clark DJ, Lipworth BJ "Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients.

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